An intertrochanteric hip fracture were calculated and are presented in figure 1: 1) a patient who was delirious from one day before operation until eight days after operation (continuously delirious), 2) a patient who was never delirious during this period (continuously non-delirious), and 3) a patient who was delirious from the day after operation until postoperative day fourTable 2: S100B (g/L) and NSE (ng/mL) values during delirium versus no delirium.(delirious day 1?). S100B levels were highest 'during' delirium at all time-points. 'Before' and 'after' delirium S100B levels were still higher than those from 'non-delirious' patients. Delirious state was not significant in the same mixed model analysis with NSE in 233 samples. Spearman's rho test showed no significant correlation between S100B and NSE levels in the first sample (p = 0.99). In 34 delirious patients, delirium subtype was specified; one patient did not meet the criteria for any of the subtypes (Table 3). Specification of the subtype was missing for 23 delirious patients and from five patients no blood sample was taken during delirium. Delirious patients with known subtype were similar to delirious patients with unknown subtype with respect to age, sex and cognitive impairment, day of PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/25751659 blood withdrawal, pre- or postoperative status and type of fracture. No large difference was observed in NSE and S100B levels in patients with different subtypes, nor was there a difference in levels between patients with known vs. unknown subtype. Of 38 patients the severity of delirium (DRS-R-98) was specified. Spearman's test revealed no significant correlation between levels of DRS-R-98 and NSE (r = 0.20, p = 0.32) or S100B (r = -0.08, p = 0.62).During delirium (N = 57*) NSE ?number N ( ) > 12.5 Mean (SD) S100B ?number N ( ) > 0.10 Median (IQR) 35 9 (26) 11.7 (3.8) 57 46 (81) 0.16 (0.10?.25)No delirium (N = 58) 40 15 (38) 11.7 (4.7) 58 29 (50) 0.10 (0.08?.15)p-value0.28 0.97 0.001 Capecitabine frequency of delirium (52 ) has been found in other large studies of hip fracture patients[29]. The expected risk factors for delirium in surgical patients, such as functional and cognitive impairment, were confirmed in our study[30]. Next to delirium, type of fracture, pre-.